MMS: A “R” Package for Metabolomic Markers Search in Stress Re- sponse Studies

نویسندگان

  • G. Cardinali
  • P. Rellini
  • C. Pelliccia
  • L. Antonielli
  • F. Fatichenti
چکیده

In stress response studies, metabolomics tries to individuate spectral areas or metabolites whose response to a specific stress is particularly significant. This evaluation is normally carried out with a series of tedious and time consuming comparisons of spectral areas obtained from cells subject to different stress intensities. MMS is a package written in “R” language able to individuate which part of metabolomic spectra have a statistically significant response giving as output the diagrams of the R 2 and of the slope calculated from regression analysis between a vector describing the intensity of the stress and a matrix containing all spectra from differently challenged cells.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Factors Affecting Information Search Behavior in Purchasing an Outbound Package Tour: A Thematic Analysis

The present study seeks to examine the factors affecting information search of heads of households in purchasing an outbound package tour. A sample of 60 academics and non-academics in the field of tourism was chosen. Sampling methods were judgmental and snowball sampling. In order to gather data, we used a semi-structured interview.  Thematic analysis was applied for data analysis, and the col...

متن کامل

Effects of Diesel Combustion Nanoparticles on Oxidative Stress Markers among the Exposures

Background: Although studies are available on lipid peroxidation products and the antioxidant status in experimental animals, a detailed report on human exposed to diesel combustion nanoparticles is meagre. We aimed to study the variation in oxidative stress markers among exposures. Method:A cross-sectional study during the period between 2015-2017 was conducted among 500 male garage workers of...

متن کامل

Emerging Applications of Metabolomic and Genomic Profiling in Diabetic Clinical Medicine

Clinical and epidemiological metabolomics provides a unique opportunity to look at genotype-phenotype relationships as well as the body\x{2019}s responses to environmental and lifestyle factors. Fundamentally, it provides information on the universal outcome of influencing factors on disease states and has great potential in the early diagnosis, therapy monitoring, and understanding of the path...

متن کامل

Meta-Analysis in R Using Package rmeta

Meta-Analysis means a statistical analysis on the results of their findings is to combine a large number of independent studies. Meta-Analysis software is needed to be done for convenience, Statistical Software for Meta-Analysis is available in many statistical packages available in the present study provide software R is for Meta-Analysis. First, a brief description of the Meta-Analysis, Stati...

متن کامل

Relationship between Serum Levels of Anti-Mullerian Hormone, Adiponectin and Oxidative Stress Markers in Patients with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Anti-Mullerian hormone (AMH) is a valid indicator of ovarian function and is used for PCOS diagnosis. Some studies have shown that adipokines affect the synthesis of AMH, and therefore they are somehow related in function. The aim of the present study was to determine the relationshi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2008